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A) Heatmap showing expression of <t>FGFR1/3</t> and FGF2/9 across a panel of cell lines derived from MCL, ABC-DLBCL, and germinal center B-cell (GCB) DLBCL; heatmap is based on log2 CPM (counts per million). The scale ranges from low (-4, blue) to high (+4, red). Each horizontal represents the values for one cell line. B) Immunoblot for <t>FGFR1</t> <t>protein</t> in a subset of selected cell lines and C) its protein quantification expressed as a ratio to SP53; data is the average with the second replicate shown in Supplementary Figure 1.
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A) Heatmap showing expression of FGFR1/3 and FGF2/9 across a panel of cell lines derived from MCL, ABC-DLBCL, and germinal center B-cell (GCB) DLBCL; heatmap is based on log2 CPM (counts per million). The scale ranges from low (-4, blue) to high (+4, red). Each horizontal represents the values for one cell line. B) Immunoblot for FGFR1 protein in a subset of selected cell lines and C) its protein quantification expressed as a ratio to SP53; data is the average with the second replicate shown in Supplementary Figure 1.

Journal: bioRxiv

Article Title: Targeting Aberrant FGFR Signaling with Infigratinib Enhances the Efficacy of BTK/PI3K Inhibitors and Bendamustine in Lymphoma Cells

doi: 10.64898/2025.12.23.695986

Figure Lengend Snippet: A) Heatmap showing expression of FGFR1/3 and FGF2/9 across a panel of cell lines derived from MCL, ABC-DLBCL, and germinal center B-cell (GCB) DLBCL; heatmap is based on log2 CPM (counts per million). The scale ranges from low (-4, blue) to high (+4, red). Each horizontal represents the values for one cell line. B) Immunoblot for FGFR1 protein in a subset of selected cell lines and C) its protein quantification expressed as a ratio to SP53; data is the average with the second replicate shown in Supplementary Figure 1.

Article Snippet: The following primary antibodies were used in TBST 5% BSA buffer: FGFR1 mouse monoclonal (M19B2) (NB600-1287, Novus),Bek/FGFR2 mouse monoclonal (C-8) (sc-6930, Santa Cruz), FGFR3 mouse monoclonal (MAB766-100, ReD) and FGFR-4 mouse monoclonal (A-10) (sc-136988, Santa Cruz).

Techniques: Expressing, Derivative Assay, Western Blot